RB Prod Tech Kov/B94 Cell Culture III [Graveyard shift Sun-Wed 2100-0730] (Houston)

Bayer in Houston, TX

  • Industry: Scientific Research - Biology/Bioengineering
  • Type: Full Time
  • $66,940.00 - 178,640.00
position filled
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Job Description

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At Bayer you have the opportunity to be part of a culture where we value the passion of our employees to innovate and give them the power to change.

RB Prod Tech Kov/B94 Cell Culture III [Graveyard shift Sun-Wed 2100-0730]


The primary responsibilities of this role, RB Production Tech Kov/ B94 Cell Culture III, are to:

  • Prepare process equipment (including but not limited to Bioreactors and ancillary equipment, Stainless Steel tanks, Pressure Transmitters, Flow Meters, Aggregate traps, Harvest discards, Transfer lines (buffers, cTCF), Hoses and small parts;

  • Clean and Sterilize equipment using appropriate CIP (Clean-In-Place), SIP (Steam-In-Place) procedures;

  • Perform daily or routine process operations in the cell culture and purification of biotech and biological products (Kovaltry, Kogenate, and Jivi) and operate equipment for these processes;

  • Inoculate and monitor bioreactors;

  • Process cTCF material to Continuous Cell Separation (CCS);

  • Operate Chromatography, MAEF, MAVF and TFF skids;

  • Process MAEF material using closed thaw process, step elution chromatography, Membrane Absorber and filter clearance technology, and gradient controlled SP column separation techniques;

  • Operate 50L, 200L and 1000L collection bag technology to ensure robust collection, mixing and dilution of products.

  • Perform PEGylation of JIVI in process material using TFF technology;

  • Operate automated bagging systems;

  • Blast Freezes product for storage;

  • Dispense chemicals and formulate solutions;

  • Prepare acids and bases as necessary;

  • Perform aseptic operations;

  • Take, analyze and submit samples as required throughout the process;

  • Monitor and control operation with computer control systems;

  • Complete all routine check sheets;

  • Clean equipment and maintain clean and orderly production facilities;

  • Perform in-depth troubleshooting and root cause analysis of Kovaltry, Kogenate, and Jivi equipment and process failures;

  • Contribute to continuous improvement opportunities;

  • Perform all operations in compliance with current Good Manufacturing Practices (cGMP);

  • Perform other related duties as assigned.


    Your success will be driven by your demonstration of our LIFE values. More specifically related to this position, Bayer seeks an incumbent who possesses the following:

    Required Qualifications:

  • At least two-years' College science courses (e.g. biology, chemistry, biochemistry, or microbiology), or a certificate from an accredited bio-technology academy;

  • Acceptable attendance and performance;

  • Orientation to detail;

  • Good verbal and written communication skills;

  • Ability to read, write, speak, and comprehend English in order to understand written and verbal instructions, SOP's, BPR's, etc;

  • Ability to demonstrate good record keeping practices and follow data integrity rules;

  • Ability to troubleshoot and control processes;

  • Ability to work both independently/self-directed with minimal supervision and in a team environment;

  • Ability to cope with fast paced operations and repeatedly perform multi-step simultaneous operations with high degree of accuracy;

  • Ability to work under BC III (Class 100,000) gowning conditions;

  • Ability to lift up to =50 lbs. and push/pull up to 400 lbs. with assistance;

  • Ability to withstand frequent repetitive movement, stooping, crouching, kneeling, climbing (ladders), and sitting;

  • Ability to work in cold rooms;

  • Ability to differentiate color in order to monitor DCS computer and identify items using color-coded labels;

  • Computer skills, including: the ability to learn software applications such as the learning management system (LMS), document control, e-mail (Outlook), Sentry DR/CAPA System, etc;

  • Must meet Occupational Demands/Physical Requirement checklist;

  • Must take Blood test for Hepatitis B and get vaccine;

  • Must not have unusual sensitivity to typical lab chemicals or gloves (i.e. sanitizing agents), use required chemicals and wear protective clothing (PPE) and gowning as required.

  • Preferred Qualifications:

  • Relevant bio-tech industry experience in some or all of the following may be considered in lieu of some or all of the educational requirements above:

  • Cell Culture bioreactor system assembly and use, including control of gas supply to bioreactor, Micro-sparger assembly, Anti-Foam Emulsion system;

  • Continuous Cells Separation equipment preparation and process/controls;

  • Membrane Absorption Chromatography process (e.g. Membrane Absorption process, Buffer and NaOH supply, cTCF supply, Capsule preparation, Inline dilution and Temperature controls);

  • Basic knowledge of protein chemistry and purification systems such as anion, cation, and immunoaffinity chromatography;

  • Membrane Absorber technology, viral removal techniques and tangential flow filtration technology. Large scale chromatography, TFF technology;

  • Familiarity with cGMP's and applicable agency regulations.


    Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and you have the "Passion to Innovate" and the "Power to Change", we encourage you to apply now. To all recruitment agencies: Bayer does not accept unsolicited third party resumes.

    Bayer is an Equal Opportunity Employer/Disabled/Veterans

    Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.

    Location: United States : Alabama : Birmingham || United States : Alabama : Centre || United States : Alabama : Huntsville || United States : Alabama : Loxley || United States : Alabama : Mobile || United States : Alabama : Piedmont || United States : Alabama : Residence Based || United States : Alaska : Anchorage || United States : Alaska : Residence Based || United States : Arizona : Casa Grande || United States : Arizona : Chandler || United States : Arizona : Eloy || United States : Arizona : Glendale || United States : Arizona : Maricopa || United States : Arizona : Peoria || United States : Arizona : Phoenix || United States : Arizona : Residence Based || United States : Arizona : Tucson || United States : Arkansas : Bentonville || United States : Arkansas : DeWitt || United States : Arkansas : Harrisburg || United States : Arkansas : Jonesboro || United States : Arkansas : Little Rock || United States : Arkansas : Marion || United States : Arkansas : North Little Rock || United States : Arkansas : Residence Based || United States : Arkansas : Rogers || United States : Arkansas : Stuttgart || United States : California : Acampo || United States : California : Anaheim || United States : California : Arroyo Grande


    Associated topics: bacteria, bio, bioengineering, biology, biostatistics, physical, physiology, stem cell, toxicologist, virus

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